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Different kinds of twinsTwins are either
identical or fraternal. However, more important
for the outcome of the pregnancy is whether the babies share a
single placenta or afterbirth (monochorionic twins) or
whether there is one placenta for each baby (dichorionic
twins).
The majority of twins are dichorionic where each baby
has his/her own placenta. Most dichorionic twins are
fraternal, resulting from the fertilisation of two
different eggs by two different sperms. They may
look as similar or as different as any two siblings would and may
have the same or opposite sex. They are like brother and sister
who happen to occupy the same womb at the same time. Only a
minority of dichorionic twins with the same sex will
identical.
Monochorionic twins are always identical
twins, who result from the fertilisation of a single egg
by a single sperm, followed by early division of the
fertilised ovum into two halves, which develop separately. The
resulting children are very similar in appearance and by
definition have the same sex, as they carry the same
genes.
Prior to the 14th week of pregnancy (duration of
pregnancy = 40 weeks), the distinction between
monochorionic and dichorionic twins can be made
on ultrasound scan with a 100% accuracy. Later on in pregnancy it
becomes far more difficult and often not possible at all to
determine whether same sex twins do or do not share a common
placenta. Only examination of the placenta after birth will then
give the answer.
Why is it important to distinguish monochorionic from
dichorionic twins?It is of vital importance for the
following reasons:
Monochorionic twin pregnancies have a much higher risk
for complications than dichorionic twin pregancies,
because two babies have to grow on a single placenta, which is
often not equally divided between both twins. Furthermore, their
blood circulations are connected through blood vessels in the
common placenta and blood may pass disproportionately from one
baby to the other, leading to the twin -twin transfusion syndrome
(TTTS). Identification of this high-risk group, will allow for a
more careful surveillance of pregnancy.
What are the risks of a twin pregnancy?
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A too early deliveryThis is the most common problem
of a twin pregnancy. About half of twins are born before 37
weeks. When born after 32 weeks, babies may still have
feeding and breathing problems, but they will nearly always
survive. In contrast, babies born between 24 and 32 weeks
have a high risk of dying or handicap if they survive. The
median gestational age of delivery is only marginally earlier
in monochorionic (36 weeks) compared with
dichorionic twins (37 weeks). However, the
proportion of pregnancies delivering very early (before 32
weeks) is nearly twice as high in monochorionic (9%)
compared with dichororionic twins (5.5%).
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Poor growth of the babiesIn twins, the risk of
delivering growth-restricted babies is about 10 times higher
than in singletons. The chance of both babies growing poorly
is about 4 times as high in monochorionic (7.5%)
compared with dichorionic (2%) pregnancies. It may
also happen that that one baby is much smaller than the
other. This problem seems to affect monochorionic
twins (11%) as often as dichorionic (12%) twins,
although the underlying cause, the consequences and the
management are different. As mentioned above, most
dichorionic twins are fraternal and thus genetically
different. As such, genetic causes may explain the growth
difference. Also, both twins have their own placenta and it
may be that one placenta does not work as well as the other.
In contrast, monochorionic twins are carrying the
same genes and are on the same placenta, so there must be
other reasons why one baby grows better than the other.
Firstly, the placenta is often not equally divided between
both twins with usually the bigger twin having the largest
part of the placenta. Secondly, because the blood
circulations of both babies are connected in the single
placenta, one baby may continuously transfer small amounts of
blood and thus oxygen and nutrients to the other and
therefore grow poorly. If growth is faltering for one or both
babies, then their well being will be followed closely.
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Twin-twin transfusion syndrome (TTTS): a complication
unique to monochorionic twins:In monochorionic
twins, the blood vessels that connect the blood circulations
of both babies will cause no problems, as long as the
distribution of blood supply is well balanced. However, may
happen that more blood is directed from one baby towards the
other, leading to TTTS. The first baby is called then the
donor since he essentially pumps his blood into the second
baby, who is called the recipient. The donor usually suffers
from anaemia (too little blood), hypovolemia (too little
fluid) and is frequently smaller. Due to a deficiency in
blood and fluid, the donor will produce less urine. Since
urine is the main constituent of the amniotic fluid, the
amniotic fluid around the donor will decrease
(oligohydramnios), eventually disappearing altogether. The
donor will appear to be almost shrink-wrapped and
‘stuck’ up against the wall of the womb, which
explains why the donor is often called the ‘stuck
twin’. Meanwhile, the recipient has his own worries. He
receives too much blood and eliminates the excess fluid by
increasing his urine production. This causes too much
amniotic fluid around the recipient (polyhydramnios) and a
rapid and excessive distension of the womb, leading to a too
early delivery or rupture of the membranes. TTTS complicates
about 15% of monochorionic twin pregnancies usually
between 16 and 24 weeks of gestation. If TTTS is not picked
up and left untreated, it is likely to cause loss of both
babies. The two currently most performed treatments are
drainage of the excessive fluid or surgical separation of the
connecting vessels on the placenta is performed by means of
laser.
SummarisingTwins, especially if monochorionic ,
still pose specific challenges. Fortunately, most twin
pregnancies do well and do NOT pose any of these problems. By
necessity, this leaflet focused on things that can go wrong to
alert parents on areas where concern may arise, because
well-informed parents make the best partners in the care for
their unborn babies.
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